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Դڿ http://www.qikan.com.cn ͡*ȵ*ƻ͸֬Ѫ֢ Ч۲ ߣ ξ Դйҽҩѧ2012 14 [ժҪ] Ŀ ̽͡*ȵ*ƻ͸֬Ѫ֢ٴЧ 106 ͸֬Ѫ֢Ϊ飬 53 ͡ƣ۲ 53 ڶ ƵĻϼðȵ*ơ 8 Ϊ 1 Ƴ̣۲ǰѪ֬仯Ͳ Ӧ ̴ܵܶ֬׵̴ǰ½۲ Ϊܶ֬׵̴ߣP0.05ӦȽϲͳ ѧ壨P0.05 ͡*ȵ*ƻ͸֬Ѫ֢нϺõĵ֬ ãȫɿЧֵٴƹӦá [ؼ] ͸֬Ѫ֢͡ȵ* [ͼ] R589.2 [ױʶ] B [±] 2095-0616201214-36-03 Observation of the curative effect on the simvastatin and amlodipine treatment for combined hyperlipidemia familial WU Rui HE Jiuming Department of Internal Medicine,the Fifth People''s Hospital of Foshan,Foshan 528211,China [Abstract] Objective To discuss the clinical effect of the simvastatin and amlodipine treatment for combined hyperlipidemia familial. Methods 106 patients with combined hyperlipidemia familial were divided into two groups,53 patients in the control group were treated by simvastatin,the other 53 patients in the observation group were treated by amlodipine on the basis of the control group,8 weeks for one course,and then observed the blood-lipid change and untoward effect after and before treatment in two groups. Results The total cholesterol,low density lipoprotein cholesterin and triglycercide were all changed more than before treatment,the observation group was more notable than the control group,and the high density lipoprotein-cholesterol was raised(P0.05).The untoward effect was no different statistical significance in two groups(P0.05). Conclusion The simvastatin combined with amlodipine treats the combined hyperlipoidemia familial, which can modulate the blood-lipid,it is safe and reliable,best efficiency and worth spreading and applicating in clinical. [Key words] Combined hyperlipoidemia familial;Simvastatin;Amlodipine ֬Ѫ֢ɶӲĹؼ֮һӲġѪܼĻ 䡣ˮ*ߣѪܲữѪֳ֬ΪĶ෢ Դڿ http://www.qikan.com.cn ʶҩԽԽܵصע[1]ģٴо֤ʵ͡ҩɽѪ ķʺͲʡڻ֬쳣͡ҩѪ֬Դ[2]߲ ͡*ȵ*ƻ͸֬Ѫ֢Чֱ¡ 1 뷽 1.1 һ ѡ 2010 6 ¡2011 12 ڼڱҽԺľйIJIJΣ Ļ͸֬Ѫ֢ 106 68 Ů 38 4580 ꣬*56.96.2 ꡣ֬Ѫ֢ݡ2006 йѪ֬쳣ָϡ[3]̴ܵTC5.7 mmol/LTG1.70 mmol/L ң4.52 mmol/LHDL-C1.04 mmol/Lܶ֬ ׵̴LDL-C4.14 mmol/L ΪԸ֬Ѫ֢ 106 Ϊ۲ 飬黼Ա䡢ʷѪǡѪܼ֬ϲʹóҩȷ Ƚϲͳѧ壨P0.05пɱԡ 1.2 ų׼ 12 ڷ͡κν֬ҩP*ġѪܼ¼2 ҪӰѪ֬



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